4/6/2023 0 Comments Mitosis flip book pdfThese two increases affect most of the H1 molecules and thus reflect phosphorylations occurring widely throughout the chromatin, presumably in association with replication and mitotic chromosome condensation. phosphorylation levels of approximately 1 P/mol during the S phase and a further increase or 3-4 P/mol during mitosis. Both subtypes undergo a general increase in. In G1 cells, the H1 molecules are distributed among several phosphorylation states, most H1A molecules containing 0 or 1 phosphate groups and most H1B molecules containing 0, 1, 2, or 3 phosphate groups. The histone 1 (H1) fraction of HeLa S-3 cells contains two principal subtypes, H1A (Mr approximately 21 000) and H1B (Mr approximately 22 000).
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